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pentobarbital will minimize the level or influence of fosphenytoin by affecting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Monitor.

pentobarbital will minimize the level or outcome of copyright topical by impacting hepatic enzyme CYP2B6 metabolism. Minimal/Significance Unknown.

pentobarbital will decrease the level or outcome of ramelteon by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Not known.

pentobarbital will minimize the extent or outcome of lapatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

pentobarbital will decrease the level or outcome of cinacalcet by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.

pentobarbital will lower the level or impact of quinine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Mysterious.

pentobarbital will lessen the level or impact of lefamulin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Prevent coadministration of lefamulin with solid or moderate CYP3A inducers Unless of course the advantage outweighs risks. Monitor for decreased efficacy.

pentobarbital will minimize the extent or check here impact of imatinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.

pentobarbital will lessen the level or impact of buspirone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

pentobarbital decreases amounts of amphotericin B deoxycholate by inhibition of GI absorption. Applies only to oral method of the two agents. Minor/Importance Mysterious.

pentobarbital will lower the level or impact of trazodone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

Administer barbiturates with caution in patients with hepatic problems and at reduced doses initially; barbiturates really should not be administered to people exhibiting the premonitory signs of hepatic coma

Observe Carefully (one)pentobarbital will reduce the level or result of tofacitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Loss of, or decreased response to tofacitinib may well take place when coadministered with powerful CYP3A4 inducers

Monoamine oxidase inhibitors (MAOI) may perhaps inhibit barbiturate metabolism and prolong barbiturate effects; check carefully